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Estrogen signaling in cancer microenvironment and prediction of response to hormonal therapy

✍ Scribed by Shin-ichi Hayashi; Yuri Yamaguchi


Book ID
116698178
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
619 KB
Volume
109
Category
Article
ISSN
0960-0760

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This review presents our experience with the use of estrogen receptors (ER) and progesterone receptors (PgR) in the prediction of response to endocrine therapy in stage IV breast cancer. Presence of ER (>3 fmoUmg cytosol protein) significantly predicted response to the antiestrogen tamoxifen and to