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Estrogen receptor beta agonist diarylpropiolnitrile (DPN) does not mediate neuroprotection in a rat model of permanent focal ischemia

โœ Scribed by Tracy D. Farr; Hilary V.O. Carswell; Willy Gsell; I. Mhairi Macrae


Book ID
113503071
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
515 KB
Volume
1185
Category
Article
ISSN
0006-8993

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Neuroprotective effects of prostaglandin
โœ Hui-Ling Zhang; Zhen-Lun Gu; Sean I. Savitz; Feng Han; Kohji Fukunaga; Zheng-Hon ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 822 KB

## Abstract We have previously reported that prostaglandin A~1~ (PGA~1~) reduces infarct size in rodent models of focal ischemia. This study seeks to elucidate the possible molecular mechanisms underlying PGA~1~'s neuroprotective effects against ischemic injury. Rats were subjected to permanent mid