Estrogen receptor analysis in primary breast tumors by ligand-binding assay, immunocytochemical assay, and northern blot: a comparison
β Scribed by Marc Lacroix; Gilbert Querton; Philippe Hennebert; Denis Larsimont; Guy Leclercq
- Book ID
- 110367560
- Publisher
- Springer US
- Year
- 2001
- Tongue
- English
- Weight
- 125 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0167-6806
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Evaluation of estrogen (ER) and progesterone (PR) receptor content is now an important procedure in the management of breast cancer patients. Production of monoclonal antibodies to ER and PR has permitted development of an enzyme immunoassay (EIA) and immunocytochemical assay (ICA). This study compa
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Results of estrogen receptor (ER) and progesterone receptor (PgR) ligand-binding assays (LBAs) are strongly correlated with ER and PgR by immuno-histochemistry (IHC). To investigate whether ER and PgR by IHC are also strongly correlated with tamoxifen response, time to treatment failure (TTF) and ov