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Estrogen receptor alpha polymorphism is associated with pelvic organ prolapse risk

✍ Scribed by Huey-Yi Chen; Ya-Wen Chung; Wei-Yong Lin; Wei-Chi Chen; Fuu-Jen Tsai; Chang-Hai Tsai

Publisher: Springer
Year: 2008
Tongue: English
Weight: 100 KB
Volume: 19
Category: Article
ISSN: 0937-3462
DOI: 10.1007/s00192-008-0603-1

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## Abstract Estrogens exert their effect on the breast through the estrogen receptor. We prospectively investigated breast cancer risk associated with 2 polymorphic sites in the estrogen receptor alpha gene (__ESR1__). A total of 4,248 Caucasian women from the Study of Osteoporotic Fractures were g