𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Estrogen and progesterone receptors in cervical human papillomavirus related lesions

✍ Scribed by Joseph Monsonego; Henri Magdelenat; François Catalan; Yves Coscas; Laurent Zerat; Xavier Sastre

Publisher
John Wiley and Sons
Year
1991
Tongue
French
Weight
907 KB
Volume
48
Category
Article
ISSN
0020-7136

No coin nor oath required. For personal study only.

✦ Synopsis

According to recent studies showing that human papillomavirus (HPV) infections can be influenced by sex steroid hormones, we performed estrogen (ER) and progesterone (PgR) receptor assays in fresh frozen biopsies of genital-HPV-related lesions. Seventy-three women with normal cervix, condyloma, low-and high-grade CIN and squamous carcinoma were evaluated in comparison with I 5 persons with vulvar and 9 with penile papillomavirus-associated lesions. HPV genotypes were determined by dot-blot hybridization. Non-cervical lesions did not express HR. Condyloma on squamous metaplasia of the cervix and high-grade CIN expressed high levels of HR, particularly PgR (mean 4,086 and 4,518 fmolew'g tissue, respectively). Cervical squamous carcinoma expressed very low concentrations of PgR in a limited number of cases. High levels of PgR were correlated with high-grade CIN (p < 0.05), HPV 16-18-associated lesions (p < 0.0 I) and ER were correlated to HPV6-I I -related lesions (p < 0.0 I). The 5To whom correspondence and reprint requests should be sent

📜 SIMILAR VOLUMES

Estrogen and progesterone receptors in h
Estrogen and progesterone receptors in human gallbladder
✍ Brian K. Singletary; David H. van Thiel; Patricia K. Eagon 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 English ⚖ 551 KB

Gallbladder disease is more prevalent in women than men. Estrogen therapy has been associated with an increased incidence of gallbladder disease in both sexes. Further, increased progesterone levels have been implicated in impairment of gallbladder motility in pregnancy. Because sex hormones often e

Prevalence and genotype distribution of
Prevalence and genotype distribution of human papillomavirus in non-neoplastic cervical tissue lesion: Cervical erosion
✍ Aysen Bayram; Suna Erkılıç; Özcan Balat; Fahriye Ekşi; Mete Gürol Uğur; Ebru Özt 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 92 KB

## Abstract Human papillomavirus (HPV) infection is the commonest sexually transmitted infection, which is associated with various clinical conditions, ranging from asymptomatic infection to malignant disease of the cervix. The aim of this study was to evaluate the prevalence and genotypic distribu

Estrogen and progesterone receptors in b
Estrogen and progesterone receptors in benign breast tumors and lesions: Relationship with histological and cytological features
✍ C. Giani; E. D'Amore; J. C. Delarue; H. Mouriesse; F. May-Levin; H. Sancho-Garni 📂 Article 📅 1986 🏛 John Wiley and Sons 🌐 French ⚖ 444 KB

The pattern of estrogen (ER) and progesterone receptors (PR) and their relationship to histo- and cyto-pathological parameters has been studied in 97 cases of benign breast disease and benign phyllode tumors (95 women, of whom 76 were premenopausal, and 2 men). Total (cytosolic + nuclear) ER and PR

Quantitative human papillomavirus 16 and
Quantitative human papillomavirus 16 and 18 levels in incident infections and cervical lesion development
✍ Rachel L. Winer; Tiffany G. Harris; Long Fu Xi; Kathrin U. Jansen; James P. Hugh 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 108 KB

## Abstract Human papillomavirus (HPV) RNA levels may be a more sensitive early indicator of predisposition to carcinogenesis than DNA levels. We evaluated whether levels of HPV‐16 and HPV‐18 DNA and messenger RNA (mRNA) in newly detected infections are associated with cervical lesion development.

Human papillomavirus-31-related types pr
Human papillomavirus-31-related types predict better survival in cervical carcinoma
✍ Lee-Wen Huang; Shiouh-Lirng Chao; Jiann-Loung Hwang 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 95 KB

## Abstract ## BACKGROUND The aim of the current study was to explore the clinical implications and prognostic value of human papillomavirus (HPV) genotype in cervical carcinomas. ## METHODS A total of 152 patients diagnosed with International Federation of Gynecology and Obstetrics Stage I–IV c