The inability of young female guinea pigs to display progesterone-facilitated lordosis has been attributed, in part, to a deficiency in the concentration of hypothalamic estradiol-induced progestin receptors, as measured by in vitro binding assays. An immunocytochemical technique was used to ascerta
โฆ LIBER โฆ
Estradiol pulses induce progestin receptors selectively in substance P-immunoreactive neurons in the ventrolateral hypothalamus of female guinea pigs
โ Scribed by Olster, Deborah H. ;Blaustein, Jeffrey D.
- Publisher
- John Wiley and Sons
- Year
- 1992
- Tongue
- English
- Weight
- 882 KB
- Volume
- 23
- Category
- Article
- ISSN
- 0022-3034
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Pulsatile administration of estradiol effectively primes orchidectomized ( O R C H ) male guinea pigs to display progesterone-facilitated lordosis. In contrast, a single injection of estradiol benzoate ( E B ) is not behaviorally effective. In ovariectomized female guinea pigs, estradiol pulses indu