Estradiol-mediated internalisation of the non-activated estrogen receptor from the goat uterine plasma membrane: Identification of the proteins involved
β Scribed by S. Sreeja; Raghava Varman Thampan
- Book ID
- 111598603
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 216 KB
- Volume
- 259
- Category
- Article
- ISSN
- 0300-8177
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## Abstract A 66 kDa transport protein, tp66, has been identified as the protein that mediates the nuclear transport of the estrogen receptor activation factor (EβRAF). Indirect evidence shows that tp66 influences the transport of EβRAF mainly by recognizing the nuclear localization signals (NLS) o
## Abstract The primary intracellular site of localization of the estrogen receptor activation factor (EβRAF) is shown here to be the endoplasmic reticulum where the protein remains anchored through an estrogen dependent mechanism. The retention of EβRAF by the endoplasmic reticulum is facilitated