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Estradiol inhibits hyaluronic acid synthase 1 expression in human vascular smooth muscle cells

✍ Scribed by Till Freudenberger; Katharina Röck; Guang Dai; Selma Dorn; Peter Mayer; Hans-Karl Heim; Jens W. Fischer

Book ID
106067338
Publisher
Springer
Year
2011
Tongue
English
Weight
513 KB
Volume
106
Category
Article
ISSN
0300-8428

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## Abstract Myocardin, a cofactor of serum response factor (SRF), specifically induces the expression of contractile proteins to promote differentiation and contractile phenotype of smooth muscle cells (SMCs). SRF directly induces the transcription of microRNA‐1 (miR‐1) in cardiac and skeletal musc