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Estradiol inhibits atp-induced intracellular calcium concentration increase in dorsal root ganglia neurons

โœ Scribed by V.V Chaban; E.A Mayer; H.S Ennes; P.E Micevych


Book ID
117490986
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
220 KB
Volume
118
Category
Article
ISSN
0306-4522

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Estradiol attenuates the ATP-induced increase of intracellular calcium concentration ([Ca(2+)](i)) in rat dorsal root ganglion (DRG) neurons by blocking the L-type voltage gated calcium channel (VGCC). Because ATP is a putative nociceptive signal, this action may indicate a site of estradiol regulat