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Estradiol ameliorates arthritis and protects against systemic bone loss inStaphylococcus aureusinfection in mice

✍ Scribed by Inger Gjertsson, Marie K Lagerquist, Erik Kristiansson…


Book ID
120706089
Publisher
BioMed Central
Year
2012
Tongue
English
Weight
554 KB
Volume
14
Category
Article
ISSN
1478-6354

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✍ Petra Herrak; Birgit Görtz; Silvia Hayer; Kurt Redlich; Erika Reiter; Jürg Gasse 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 589 KB

## Abstract ## Objective Increased osteoclast activity is a key factor in bone loss in rheumatoid arthritis (RA). This suggests that osteoclast‐targeted therapies could effectively prevent skeletal damage in patients with RA. Zoledronic acid (ZA) is one of the most potent agents for blocking osteo