Estimation of Trichoderma QM 9414 biomass and growth rate by indirect means

Automatic inducer addition and harvestin

Automatic inducer addition and harvesting of recombinant Escherichia coli cultures based on indirect on-line estimation of biomass concentration and specific growth rate

✍ Niels Thomas Eriksen; Irina Kratchmarova; Søren Neve; Karsten Kristiansen; Jens 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 English ⚖ 176 KB 👁 2 views

## Abstract This article describes a novel bioreactor configuration for production optimization of recombinant proteins in __Escherichia coli__. Inducer addition and harvesting are controlled on‐line based on indirect estimation of biomass concentration and specific growth rate from addition of NaO