𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Estimation of Treatment Difference and Standard Deviation with Blinded Data in Clinical Trials

✍ Scribed by Michael Chen; Farid Kianifard

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
77 KB
Volume
45
Category
Article
ISSN
0323-3847

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

A double blind, randomized clinical tria
A double blind, randomized clinical trial assessing the efficacy and safety of augmenting standard antidepressant therapy with nimodipine in the treatment of β€˜vascular depression’
✍ Fernando E. Taragano; Ricardo Allegri; Augusto Vicario; Pablo Bagnatti; Constant πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 92 KB πŸ‘ 1 views

## Abstract ## Background β€˜Vascular depression’ may be caused by cerebrovascular disease. Calcium channel blockers, which are putative treatments for cerebrovascular disease, might be expected to improve depression reduction and to prevent recurrence of depression in this patient population. This

Assessing treatment–time interaction in
Assessing treatment–time interaction in clinical trials with time to event data: a meta-analysis of hypertension trials
✍ F. Boutitie; F. Gueyffier; S. J. Pocock; J. P. Boissel πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 178 KB πŸ‘ 3 views

Exploration of the variation of treatment effect over time in randomized clinical trials with low event rates is limited by lack of power. A meta-analysis on individual patient data from such trials can partly solve the problem, but brings other computational difficulties. Using an example in hypert

Visit-driven endpoints in randomized HIV
Visit-driven endpoints in randomized HIV/AIDS clinical trials: impact of missing data on treatment difference measured on summary statistics
✍ Emmanuelle Le Corfec; Sylvie Chevret; Dominique Costagliola πŸ“‚ Article πŸ“… 1999 πŸ› John Wiley and Sons 🌐 English βš– 133 KB

In randomized HIV/AIDS clinical trials, CD4 lymphocyte counts and plasma HIV-1 RNA measurements are often used as endpoints. The comparison between treatment groups is mainly based on a summary measure of outcome, so-called summary statistic. Such analyses are often complicated by missing data occur