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Estimation of the spin–lattice relaxation time constants of low molecular weight solutes in dilute complex aqueous solutions: application to urinary metabolites

✍ Scribed by Jeeva P. Munasinghe; Lawrence D. Colebrook; John J. Attard; T. Adrian Carpenter; Laurance D. Hall


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
246 KB
Volume
36
Category
Article
ISSN
0749-1581

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✦ Synopsis


Proton spinÈlattice relaxation rate constants values) of some selected urinary metabolites were (T 1 analysed extensively by two di †erent least-squares minimization procedures, based on the simplex and the MarquardtÈLevenberg algorithms. Comparative multiplicate analysis under di †erent experimental conditions using laboratory solutions of some of the urinary metabolites was employed in addition to direct measurements on human urine samples. The values estimated for most of the metabolites by the two methods agreed to within T 1 10È15%.