𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Estimation of the Bioavailability of Iron and Phosphorus in Cereals using a DynamicIn Vitro Gastrointestinal Model

✍ Scribed by Larsson, Marie; Minekus, Mans; Havenaar, Robert

Publisher
John Wiley and Sons
Year
1997
Tongue
English
Weight
232 KB
Volume
74
Category
Article
ISSN
0022-5142

No coin nor oath required. For personal study only.

✦ Synopsis

A recently developed in vitro gastrointestinal model was evaluated for the estimation of the bioavailability of Fe and phosphorus and its correlation with biovailability in vivo. In vitro experiments were carried out without and with phytase supplementation (750 FTU kg~1 feed) using rapeseed, sunÑowerseed, wholewheat and white wheat Ñour. Phytase addition during in vitro digestion of rapeseed and sunÑowerseed resulted in markedly increased dialysability of iron (67% and 20%) and phosphorus (31% and 66%). The release of free phosphorus during digestion of wholewheat and white wheat Ñour in the in vitro gastrointestinal model was observed to be correlated with the endogenous phytase activity in wheat. Comparison with di †erent in vivo studies revealed that the in vitro gastrointestinal model could be used for a relative estimation of the bioavailability of Fe and phosphorus.

📜 SIMILAR VOLUMES

A Stochastic Formulation of the Gompertz
A Stochastic Formulation of the Gompertzian Growth Model for in vitro Bactericidal Kinetics: Parameter Estimation and Extinction Probability
✍ L. Ferrante; S. Bompadre; L. Leone; M. P. Montanari 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 160 KB 👁 2 views

Time-kill curves have frequently been employed to study the antimicrobial effects of antibiotics. The relevance of pharmacodynamic modeling to these investigations has been emphasized in many studies of bactericidal kinetics. Stochastic models are needed that take into account the randomness of the

Model predicting the teratogenic potenti
Model predicting the teratogenic potential of retinyl palmitate, using a combined in vivo/in vitro approach
✍ Ritchie, H. E.; Webster, W. S.; Eckhoff, C.; Oakes, D. J. 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 English ⚖ 218 KB 👁 2 views

Retinyl palmitate (RP) is a known laboratory animal teratogen inducing abnormalities of the second visceral arch when administered on day 9 of gestation in the rat. However, there are significant problems when attempting to extrapolate this result to the human. A combined in vivo/in vitro model was