๐”– Bobbio Scriptorium
โœฆ   LIBER   โœฆ

Estimation of segregation and ascertainment probabilities by discarding the single probands

โœ Scribed by Dr. C. C. Li; Aravinda Chakravarti; Susan L. Halloran; D. C. Rao


Publisher
John Wiley and Sons
Year
1987
Tongue
English
Weight
350 KB
Volume
4
Category
Article
ISSN
0741-0395

No coin nor oath required. For personal study only.

โœฆ Synopsis


The first portion of this communication reiterates the method of discarding single probands for studying the segregation ratio under incomplete ascertainment. The organization of the algebra leads to the second portion, in which the "selfcontained" subsets are constructed with respect to both the segregation ratio and the ascertainment ratio. These subsets make a more detailed study of segregation and ascertainment possible.


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Dedicated t o Professor C. C. LI, in recognition of his seminal contribution to the field of human Statistical genetics ## A bstvact Procedures t o estimate the genetic segregation parameter when ascertainment of families is incomplcte, hnve previously relied on iterative computer algorithms sinc