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Estimation of Oral Bioavailability in the Rat by the Accelerated Infusion Technique

โœ Scribed by ZUYU GUO; YONGYI LUO; GLENN L. DOBSON; MICHAEL P. MARIETTA; GERALD R. RHODES; ISMAEL J. HIDALGO


Book ID
111768535
Publisher
Pharmaceutical Press
Year
2000
Tongue
English
Weight
89 KB
Volume
52
Category
Article
ISSN
2042-7158

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Effect of fruit juices on the oral bioav
โœ Amrita V. Kamath; Ming Yao; Yueping Zhang; Saeho Chong ๐Ÿ“‚ Article ๐Ÿ“… 2005 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 94 KB ๐Ÿ‘ 1 views

Fexofenadine has been identified as a substrate for both the efflux transporter, P-glycoprotein (P-gp), as well as the influx transporter, organic anion transporting polypeptide (OATP). Clinical studies in humans showed that fruit juices reduced the oral bioavailability of fexofenadine by preferenti