Estimation of left ventricular performance through temporal pressure variations measured by MR velocity and acceleration mappings
✍ Scribed by Jean-Pierre Tasu; Elie Mousseaux; Patrice Colin; Michel S. Slama; Odile Jolivet; Jacques Bittoun
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 431 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1053-1807
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✦ Synopsis
Abstract
Purpose
To describe a method for assessing pressure variation vs. time (dp/dt) using blood flow acceleration measured by MRI, and to demonstrate its applicability in estimating left ventricular (LV) function.
Materials and Methods
The method was tested in vitro using a pulsatile phantom, and a strong correlation was found between transducer and MRI determinations of dp/dt (r = 0.98). Selected aortic flow parameters were then measured in 10 patients and the results were compared with transducer measurements of the LV dp/dt.
Results
The correlation coefficients for the reference estimations of global myocardial function and MRI were 0.59 for aortic velocity, 0.74 for aortic acceleration, and 0.86 for aortic dp/dt.
Conclusion
MR measurements of velocity and acceleration within the ascending aorta offer a noninvasive method for determining indices, such as the aortic dp/dt, that are closely correlated with the global myocardial contractility function. J. Magn. Reson. Imaging 2002;16:246–252. © 2002 Wiley‐Liss, Inc.