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Estimation of Human Sperm Gene-Specific DNA Damage by Real-Time PCR Analysis

✍ Scribed by M. San Gabriel; X. Zhang; A.S. Zini

Book ID
118445754
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
49 KB
Volume
84
Category
Article
ISSN
1556-5653

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A sensitive assay for quantitating DNA damage within individual genes would be a valuable tool for identifying the molecular mechanisms of disease and the sites of action of various carcinogens and anticancer drugs. This report describes a competitive PCR assay that was used to quantitate DNA damage