Estimation of extracellular space and blood volume using bioelectrical impedance measurements

✍ Scribed by Miholic, J. ;Reilmann, L. ;Meyer, H.J. ;K�rber, H. ;Dieckelmann, A. ;Pichlmayrl, R.

• Publisher: Springer-Verlag
• Year: 1992
• Tongue: English
• Weight: 557 KB
• Volume: 70
• Category: Article
• ISSN: 1432-1440
• DOI: 10.1007/bf00184802

✦ Synopsis

The bromide-82 dilution space (extracellular space, ECS) and blood volume (BV) were measured in 21 patients with esophageal and gastric cancer and in 27 patients 18-96 months after total gastrectomy. Resistance (R) and reactance (Xc) from bioelectrical impedance measurements were used to obtain multiple regression equations for ECS and BV. The variables weight, gender, and height Z/xc were independent predictors of ECS (r = 0.767; P < 0.0001). Height 2/R and gender were predictors of blood volume (r = 0.856; P < 0.0001). The mean difference between the Br space and the ECS predicted from impedance measurements was 0 _+ 1.54 (mean ± SD). The limits of agreement ( ± 2SD) were therefore +3.081 or 19.6% of the mean Br space of 15.7 1. The limits of agreement for BV were _+789 ml or +19.7% of the average BV of 4008 ml. It is concluded that bioelectrical impedance plethysmography using a single frequency can be used for the estimation of ECS and BV. The wide limits of agreement, however, may limit its used in clinical practice.