Estimation of dynamic, in vivo soft-tissue deformation: Experimental technique and application in a canine model of tendon injury and repair
✍ Scribed by Michael J. Bey; Stephanie K. Kline; Andrew R. Baker; Jesse A. McCarron; Joseph P. Iannotti; Kathleen A. Derwin
- Publisher
- Elsevier Science
- Year
- 2010
- Tongue
- English
- Weight
- 302 KB
- Volume
- 29
- Category
- Article
- ISSN
- 0736-0266
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✦ Synopsis
Abstract
Outcomes after rotator cuff surgery are typically assessed with measures of strength, joint motion, or pain, but these measures do not provide a direct assessment of tissue function as healing progresses. To address this limitation, this manuscript describes biplane X‐ray analysis as a technique for quantifying in vivo soft‐tissue deformation. Tantalum beads were implanted in the humerus and infraspinatus tendon in a canine model of tendon injury and repair. Biplane X‐ray images were acquired during treadmill trotting and tissue deformation was estimated from the three‐dimensional bead positions. Changes over time were characterized by the mean, range, and normalized range (i.e., range/mean) of interbead distance. Intact tendon repair tissue demonstrated significant decreases over time in the mean (p = 0.003), range (p = 0.001), and normalized range (p = 0.001) of interbead distance. Failed tendon repair tissue demonstrated significant decreases over time in the range (p = 0.05) and normalized range (p = 0.04) of interbead distance. In an uninjured control, differences over time in the interbead distance parameters were not detected. This approach is a promising technique for estimating changes over time in soft‐tissue deformation. These preliminary data indicate appreciable differences between normal tendons, intact repairs, and failed repairs. © 2011 Orthopaedic Research Society Published by Wiley Periodicals, Inc. J Orthop Res 29:822–827