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Estimation of down syndrome risk in a donor egg pregnancy

✍ Scribed by Mark S. Goldberg; Herbert I. Jacobson; Theresa A. Kellom

Book ID
118832670
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
279 KB
Volume
173
Category
Article
ISSN
1097-6868

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## Abstract ## BACKGROUND Appoximately 95% of Down syndrome (DS) cases are caused by an error in germ cell division (meiosis), resulting in an extra chromosome 21. The meiotic error, predominantly of maternal origin, occurs either during the mother's fetal life (meiosis I) or at ovulation (meiosis