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Estimation of Absidia ramosa infection in the brain and kidneys of cortisone-treated mice by chitin assay

✍ Scribed by L. O. White; Helen C. Newham; J. P. Ride

Publisher: Springer Netherlands
Year: 1978
Tongue: English
Weight: 228 KB
Volume: 63
Category: Article
ISSN: 0301-486X
DOI: 10.1007/bf00490934

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✦ Synopsis

Chitin assay was used to measure Absidia ramosa infection in the brain and kidneys of cortisone-treated mice. Mice dying 3 days after challenge had brain and kidney infection but normal renal function as determined by measurement of blood urea levels. Mice dying 5 or 6 days after challenge had infection in the kidneys but not the brain and were uraemic.

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Comparison of the growth of virulent and attenuated strains of Candida albicans in the kidneys of normal and cortisone-treated mice by Chitin assay

✍ Les O. White; Ellen Gibb; Helen C. Newham; Malcolm D. Richardson; Richard C. War 📂 Article 📅 1979 🏛 Springer Netherlands 🌐 English ⚖ 295 KB

Candida albicans strain 22114 was avirulent for mice compared with strain 19321 in that, administered intravenously, 10(6) blastospores of 22114 failed to kill whereas 10(6) blastospores of 19321 produced 100% mortality. Cortisone treatment rendered mice susceptible to killing by 22114. Chitin assay