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Estimation in nonlinear mixed-effects models using heavy-tailed distributions

✍ Scribed by Cristian Meza; Felipe Osorio; Rolando De la Cruz

Book ID
106537306
Publisher
Springer US
Year
2010
Tongue
English
Weight
768 KB
Volume
22
Category
Article
ISSN
0960-3174

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✍ Cristian Meza; Florence Jaffrézic; Jean-Louis Foulley 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 147 KB 👁 2 views

## Abstract Nonlinear mixed effects models are now widely used in biometrical studies, especially in pharmacokinetic research or for the analysis of growth traits for agricultural and laboratory species. Most of these studies, however, are often based on ML estimation procedures, which are known to