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Estimation and Tests of Mendelian Inheritance in Small Samples of Human Families

✍ Scribed by Dr. M. Bchini; J. M. Goux

Publisher: John Wiley and Sons
Year: 2007
Tongue: English
Weight: 303 KB
Volume: 30
Category: Article
ISSN: 0323-3847
DOI: 10.1002/bimj.4710300610

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✦ Synopsis

Estimation of parametere in human genetics is u~ually performed by Maximum Likelihood methods for large samples relying on asymptotio results. With the aim of evaluating the importance of the bias resalting from ample size, two eeta of human family data have been analysed. The bias is not very important, but program have been elaborated, giving better eatimatione. The tests of hypotheses from these estimations have also been considered.

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