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Estimating the Unbiased Estimator θ for Population Genetic Survey Data

✍ Scribed by Jacqueline J. Weicker, Robb T. Brumfield and Kevin Winker

Book ID
125614356
Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
635 KB
Volume
55
Category
Article
ISSN
0014-3820

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## Abstract Providing valid risk estimates of a genetic disease with variable age of onset is a major challenge for prevention strategies. When data are obtained from pedigrees ascertained through affected individuals, an adjustment for ascertainment bias is necessary. This article focuses on ascer