A Bayesian method to estimate the optima
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Fabien Subtil; Muriel Rabilloud
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Article
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2010
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John Wiley and Sons
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English
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## Abstract The objective of this study was to develop methods to estimate the optimal threshold of a longitudinal biomarker and its credible interval when the diagnostic test is based on a criterion that reflects a dynamic progression of that biomarker. Two methods are proposed: one parametric and