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Estimating the optimal threshold for a diagnostic biomarker in case of complex biomarker distributions

โœ Scribed by Fabien Subtil,Muriel Rabilloud


Book ID
126375532
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
293 KB
Volume
14
Category
Article
ISSN
1472-6947

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## Abstract The objective of this study was to develop methods to estimate the optimal threshold of a longitudinal biomarker and its credible interval when the diagnostic test is based on a criterion that reflects a dynamic progression of that biomarker. Two methods are proposed: one parametric and