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Estimating the fraction reabsorbed in drugs undergoing enterohepatic circulation

✍ Scribed by F. L. S. Tse; F. Ballard; J. Skinn


Book ID
112474462
Publisher
Springer
Year
1982
Tongue
English
Weight
298 KB
Volume
10
Category
Article
ISSN
1573-8744

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## Abstract A modification of the erythrocyte partitioning method for the rapid estimation of plasma‐free drug fractions (__f__~u~) is described and applied to five basic drugs. In the procedure, which uses readily available clinical laboratory equipment, __f__~u~ is calculated from measurements of