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Estimating the effect of treatment in a proportional hazards model in the presence of non-compliance and contamination

✍ Scribed by Jack Cuzick; Peter Sasieni; Jonathan Myles; Jonathan Tyrer


Book ID
111038979
Publisher
Blackwell Publishing
Year
2007
Tongue
English
Weight
864 KB
Volume
69
Category
Article
ISSN
0952-8385

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In clinical trials where patients are randomized between two treatment arms, not all patients comply with the treatment they were randomly assigned to. The reasons for (non)compliance may be associated with the outcome variable and thereby act as confounders. The standard way of analysing such trial