𝔖 Bobbio Scriptorium
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“Estimating” heritabilities from family data

✍ Scribed by Mark G. McGee

Book ID
112475298
Publisher
Springer US
Year
1978
Tongue
English
Weight
77 KB
Volume
8
Category
Article
ISSN
0001-8244

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Estimating gene penetrance from family d
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✍ Gail Gong; Nathan Hannon; Alice S. Whittemore 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 241 KB

## Abstract Family data are useful for estimating disease risk in carriers of specific genotypes of a given gene (penetrance). Penetrance is frequently estimated assuming that relatives' phenotypes are independent, given their genotypes for the gene of interest. This assumption is unrealistic when