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Estimating genome-wide heterozygosity: effects of demographic history and marker type

โœ Scribed by Miller, J M; Malenfant, R M; David, P; Davis, C S; Poissant, J; Hogg, J T; Festa-Bianchet, M; Coltman, D W

Book ID
125445683
Publisher
Nature Publishing Group
Year
2013
Tongue
English
Weight
510 KB
Volume
112
Category
Article
ISSN
0018-067X

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## Abstract Wilms tumor (WT) is genetically heterogeneous, and the one known WT gene, __WT1__ at 11p13, is altered in only a subset of WTs. Previous loss of heterozygosity (LOH) analyses have revealed the existence of additional putative WT genes at 11p15, 16q, and 1p, but these analyses examined o