Estimate of the prevalence of chromosome 15q11-q13 duplications
โ Scribed by Thomas, N. Simon ;Roberts, S.E. ;Browne, C.E.
- Publisher
- John Wiley and Sons
- Year
- 2003
- Tongue
- English
- Weight
- 38 KB
- Volume
- 120A
- Category
- Article
- ISSN
- 0148-7299
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D u p l i c a t i o n s o f c h r o m o s o m e r e g i o n 15q11q13 often occur as a supernumerary chromosome 15. Less frequently they occur as interstitial duplications [dup(15)]. We describe the clinical and molecular characteristics of three patients with de novo dup(15). The patients, two males
## Abstract Evidence implicates the serotonin transporter gene (__SLC6A4__) and the 15q11โq13 genes as candidates for autism as well as restricted repetitive behavior (RRB). We conducted dense transmission disequilibrium mapping of the 15q11โq13 region with 93 single nucleotide polymorphisms (SNPs)