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Establishment of Immortal Hepatocytes from a CYP3A7-Transgenic/p53-Knockout Mouse

✍ Scribed by M. Shimoji; K. Hattori; S. Itoh; K. Nakayama; M. Katsuki; S. Aizawa; T. Yokoi; T. Kamataki


Book ID
115577784
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
277 KB
Volume
217
Category
Article
ISSN
0006-291X

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## Background: We demonstrated that p53-deficiency is sufficient for immortalization of fetal uterine cells. in the present study, we further extended our previous observations to prostate tissues from a young p53-deficient adult mouse. ## Methods: Cell lines were established from the ventral pro