Establishment of human osteosarcoma cell lines with high metastatic potential to lungs and their utilities for therapeutic studies on metastatic osteosarcoma

Establishment and characterization of a

Establishment and characterization of a murine osteosarcoma cell line (LM8) with high metastatic potential to the lung

✍ Tatsuya Asai; Takafumi Ueda; Kazuyuki Itoh; Kiyoko Yoshioka; Yasuaki Aoki; Shige 📂 Article 📅 1998 🏛 John Wiley and Sons 🌐 French ⚖ 245 KB 👁 2 views

We established a murine osteosarcoma cell line (LM8) with high metastatic potential to the lung from murine Dunn osteosarcoma using 8 repeated Fidler's procedures. We performed the biological characterization of the LM8 and the maternal Dunn cell lines in vitro and in vivo. Morphologically, LM8 poss