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Establishment of anti-idiotype monoclonal antibodies (Ab2β) for specific and active immunotherapy in lung cancer patients

Book ID
122409234
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
133 KB
Volume
12
Category
Article
ISSN
0169-5002

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Idiotype-anti-idiotype interactions and
Idiotype-anti-idiotype interactions and the control of the anti-β(2→6) polyfructosan response in the mouse: specificity and idiotypy of anti-ABPC48 anti-idiotypic monoclonal antibodies
✍ Pierre Legrain; Danielle Voegtle; Gérard Buttin; Pierre André Cazenave 📂 Article 📅 1981 🏛 John Wiley and Sons 🌐 English ⚖ 936 KB

## Abstract Seventeen hybridomas, secreting monoclonal anti‐idiotypic antibodies (IDA) directed against the BALB/c ABPC48 idiotype, were isolated from one immunized BALB/c mouse. Several IDA also bind another BALB/c idiotype: UPC10. ABPC48 and UPC10 are both myeloma proteins with a β(2→6)‐polyfruct