We have established human oral-squamous-cancer cell lines, BHY and HN, derived from non-metastatic cancer and metastatic cancer respectively. We examined the expression of matrix-degrading enzymes and their inhibitors in these cell lines. Both cell lines expressed pro-matrix metalloproteinase (MMP)1
โฆ LIBER โฆ
Establishment of an oral squamous cell carcinoma cell line with high invasive and p27 degradation activities from a lymph node metastasis
โ Scribed by Yasusei Kudo; Shojiro Kitajjma; Sunao Sato; Mutsumi Miyauchi; Ikuko Ogawa; Takashi Takata
- Book ID
- 114393986
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 243 KB
- Volume
- 39
- Category
- Article
- ISSN
- 1368-8375
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## Abstract Proteins of the lysyl oxidase (LOX) family are important modulators of the extracellular matrix. However, they have an important role in the tumour development as well as in tumour progression. To evaluate the diagnostic and prognostic value of the LOX protein in oral and oropharyngeal