A doxorubicin-resistant human bladder carcinoma cell line RT112/D21 was established by continuous exposure of the parental line RT112 to increasing concentrations of doxorubicin over a period of 9 months. RT112/D21 cells expressed significantly more P-170 glycoprotein than the parental line, and rho
โฆ LIBER โฆ
Establishment of a Human Small Cell Lung Carcinoma Cell Line Carrying Amplification of c-mycGene and Chromosomal Translocation of t(3p;6p) and t(12q;17p)
โ Scribed by Kato, Atsushi ;Kamiyama, Takashi ;Yamaguchi, Sachiko ;Sudo, Katsuko ;Mori, Shigeo ;Sekiguchi, Morimasa ;Aoki, Nobuo ;Shibuya, Masabumi
- Book ID
- 108579610
- Publisher
- Wiley (Blackwell Publishing)
- Year
- 1993
- Tongue
- English
- Weight
- 241 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0910-5050
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It is now well known that treatment of tumors, especially non-small-cell lung cancer (NSCLC), remains limited and it is urgent to develop strategies that target tumor cells and their genetic features. In this regard, our work is about genetic modifications arising in an in vitro NSCLC cell line afte