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Establishment of a hepatitis C virus subgenomic replicon derived from human hepatocytes infected in vitro

✍ Scribed by Nobuyuki Kato; Kazuo Sugiyama; Katsuyuki Namba; Hiromichi Dansako; Takashi Nakamura; Marika Takami; Kazuhito Naka; Akito Nozaki; Kunitada Shimotohno


Book ID
117054122
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
474 KB
Volume
306
Category
Article
ISSN
0006-291X

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Hepatitis C virus (HCV) is essentially hepatotropic, but clinical observations based on quasispecies composition in different compartments or on viral RNA detection in cells suggest that the virus is able to infect and persist in cells other than liver cells. It was shown previously that peripheral