Essentials of Thyroid Cancer Management

✍ Scribed by Robert J. Amdur MD, Ernest L. Mazzaferri MD, MACP (auth.), Robert J. Amdur MD, Ernest L. Mazzaferri MD, MACP (eds.)

• Publisher: Springer US
• Year: 2005
• Tongue: English
• Leaves: 433
• Edition: 1
• Category: Library

✦ Synopsis

Much has changed in the diagnosis and treatment of thyroid cancer over the past five years. Essentials of Thyroid Cancer Management provides clinicians from all disciplines with the information they need to manage patients correctly.

Each chapter focuses on a specific clinical situation with the major points explained using tables and figures. A teaching atlas is included for neck ultrasonography and the interpretation of whole body radioiodine scans.

Examples of topics that are covered include:

*Evaluation of a thyroid nodule

*Total versus hemi thyroidectomy

*Neck dissection for positive nodes

*Thyroid remnant ablation with I-131

*Preparation for remnant ablation with recombinant human TSH

*Follow-up with recombinant human TSH-stimulated Tg measurements

*Testing for tumor persistence

*Treatment of persistent disease

*External beam radiotherapy

*Management of distant metastases using recombinant human TSH

*Using molecular markers of medullary carcinoma

Series editor comments:

"Benign and malignant tumors of the thyroid are relatively common lesions. The management of thyroid cancer is multi-disciplinary involving Endocrinologists, Surgeons, Nuclear Medicine Physicians, and Medical and Radiation Oncologists. This text provides a comprehensive review of current management issues by leading investigators in the field."

Steven T. Rosen, M.D.
Series Editor

✦ Table of Contents

Basic Thyroid Anatomy....Pages 3-6
Thyroid and Parathyroid Physiology....Pages 7-17
Pathology and Classification Of Thyroid Carcinoma....Pages 19-31
The American Joint Committee on Cancer System of Staging Thyroid Cancer....Pages 33-36
The Diagnosis of Thyroid Cancer....Pages 39-48
Definitions: Thyroid Uptake Measurement, Thyroid Scan, and Whole Body Scan....Pages 49-54
Thyroid Stunning....Pages 55-59
The Role of a Diagnostic Radioiodine Whole Body Scan (DxWBS)....Pages 61-64
The Value of a Post-Treatment Whole Body Scan....Pages 65-68
Examples of Radioiodine Whole Body Scans....Pages 69-90
Computerized Tomography (CT) and Magnetic Resonance (MR) Imaging of Thyroid Cancer....Pages 91-94
Positron Emission Tomography (PET) of Thyroid Cancer....Pages 95-100
Neck Ultrasonography in Patients with Thyroid Cancer....Pages 101-120
Incidence, Prevalence, Recurrence, and Mortality of Differentiated Thyroid Cancer....Pages 123-130
Factors that Predict Cancer Recurrence and Death from Differentiated Thyroid Cancer....Pages 131-140
A Total Thyroidectomy Rarely Removes All Thyroid Tissue....Pages 143-145
Neck Dissections to Remove Malignant Lymph Nodes....Pages 147-151
Potential Complications of Thyroid Cancer Surgery....Pages 153-160
Half-Life and Emission Products of I-131....Pages 165-168
Choosing the Activity of I-131 for Therapy....Pages 169-175
Requirements for Outpatient Release Following I-131 Therapy....Pages 177-182
A Checklist of Things to do at the Clinic Visit Prior to I-131 Therapy....Pages 183-188
A Checklist of Things to do on the Day of I-131 Administration....Pages 189-192
Documents that Facilitate I-131 Scheduling and Patient Education....Pages 193-201
The Low-Iodine Diet....Pages 205-209
Intravenous Iodinated Contrast Effects Iodine Uptake for Months....Pages 211-213
Measuring Urinary Iodine (UI)....Pages 215-219
Using Lithium Carbonate to Increase the Effectiveness of I-131....Pages 221-227
Thyroid Hormone Withdrawal to Elevate TSH....Pages 229-231
Recombinant Human TSH: Background Information and Standard Protocol....Pages 233-237
Using rhTSH Prior to I-131 Therapy....Pages 239-246
I-131 Therapy in a Patient with a Small Thyroid Remnant....Pages 249-256
I-131 Therapy in a Patient with a Large Thyroid Remnant....Pages 257-260
Effects of Suppressing Thyrotropin on Tumor Growth and Recurrence....Pages 263-266
Potential Side Effects and Complications of I-131 Therapy....Pages 267-279
Management of Xerostomia, Taste Impairment and Dental Prophlaxis....Pages 281-283
An Overview of Follow-Up of Differentiated Thyroid Cancer....Pages 287-294
Follow-Up of Differentiated Thyroid Cancer Using Serum Thyroglobulin Measurements....Pages 295-301
Overview of Management of Differentiated Thyroid Carcinoma in Patients with Negative Whole Body Radioiodine Scans and Elevated Serum Thyroglobulin Levels....Pages 303-311
Treatment Guidelines When the Only Evidence of Disease is an Elevated Serum Thyroglobulin Level....Pages 313-316
Treatment of Residual Differentiated Thyroid Cancer in the Neck and Mediastinum....Pages 317-318
Treatment of Lung Metastases from Differentiated Thyroid Cancer....Pages 319-328
Treatment of Bone Metastases from Differentiated Thyroid Cancer....Pages 329-335
Treatment of Spinal Cord Compression from Metastatic Thyroid Cancer....Pages 337-339
Treatment of Brain Metastasis from Differentiated Thyroid Cancer....Pages 341-344
Management of Differentiated Thyroid Cancer During Pregnancy....Pages 347-350
Thyroid Cancer Originating in a Thyroglossal Duct Remnant....Pages 351-354
Tall and Collumnar Variants of Papillary Carcinoma....Pages 355-358
Diffuse Sclerosing Variant of Papillary Carcinoma....Pages 359-359
Hürthle Cell Carcinoma....Pages 361-364
Insular and other Poorly Differentiated Thyroid Carcinomas....Pages 365-367
Anaplastic Carcinoma....Pages 369-373
Diagnosis and Management of Medullary Thyroid Carcinoma....Pages 377-401
External Beam Radiotherapy Dose Schedules....Pages 405-406
Indications for External Beam Radiation Therapy for Differentiated Thyroid Cancer....Pages 407-411
Sequencing of I-131 and External Beam Radiation Therapy for Differentiated Thyroid Cancer....Pages 413-414
Indications for EBRT for Medullary and Anaplastic Thyroid Carcinoma....Pages 415-417
Conventional Radiotherapy Technique for Treating Thyroid Cancer....Pages 419-423
Intensity Modulated Radiation Therapy for Thyroid Cancer....Pages 425-431
Drawing Target Volumes for Intensity Modulated Radiation Therapy for Thyroid Cancer....Pages 433-437
Potential Toxicity of External Beam Radiotherapy for Thyroid Cancer....Pages 439-441
Resource Websites....Pages 445-446

✦ Subjects

Radiotherapy;Oncology;Endocrinology;Imaging / Radiology;Nuclear Medicine