Essentials of genomics and bioinformatics

✍ Scribed by Sensen C.W. (ed.)

• Publisher: Wiley
• Year: 2002
• Tongue: English
• Leaves: 437
• Category: Library

✦ Synopsis

Provides an overview of the rapidly evolving field of genomics with coverage of nucleic acid technologies, proteomics and bioinformatics. It includes chapters on applications in human health, agriculture and comparative genomics and also contains two chapters on the legal and ethical issues of genomics, a topic that is becoming increasingly important as genomics moves out of the laboratory into practical applications.

✦ Table of Contents

Essentials of Genomics and Bioinformatics......Page 4
Contents......Page 10
Introduction......Page 18
Application Domains......Page 20
1 Genome Projects of Model Organisms......Page 22
2 The Human Genome Project......Page 58
3 Genetic Diseases......Page 78
4 Pharmaceutical Bioinformatics and Drug Discovery......Page 122
5 Agri-Food and Genomics......Page 144
DNA Technologies......Page 162
6 Genomic Mapping and Positional Cloning, with Emphasis on Plant Science......Page 164
7 Sequencing Technology......Page 182
8 A DNA Microarray Fabrication Strategy for Research Laboratories......Page 226
Protein Technologies......Page 240
9 Two-Dimensional Gel Electrophoresis and Mass Spectrometry for Proteomic Studies: State-of-the-Art......Page 242
10 Proteome Analysis by Capillary Electrophoresis......Page 270
Bioinformatics......Page 280
11 Using the Molecular Biology Data......Page 282
12 Tools for DNA Technologies......Page 302
13 Tools for Protein Technologies......Page 326
14 Structure Information......Page 346
15 Genomic Data Representation through Images – MAGPIE as an Example......Page 362
16 Interaction Databases......Page 382
Ethical, Legal and Social Issues......Page 398
17 Ethical Aspects of Genome Research and Banking......Page 400
18 Genomics – Five Years from Now......Page 414
Index......Page 424