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Essential roles of the Fas ligand in the development of hepatitis

โœ Scribed by Kondo, Toru; Suda, Takashi; Fukuyama, Hidehiro; Adachi, Masashi; Nagata, Shigekazu

Book ID
109928167
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
623 KB
Volume
3
Category
Article
ISSN
1078-8956

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It has been postulated that tumor cells expressing Fas ligand (FasL) can evade immune surveillance by inducing apoptosis in T cells expressing Fas. In this study, we investigated FasL expression in 13 human hepatoma cell lines. Strong FasL expression was detected by reverse transcriptionpolymerase c