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Essential role of TGF-β in the natural resistance to experimental allergic encephalomyelitis in rats

✍ Scribed by Bastien Cautain; Jan Damoiseaux; Isabelle Bernard; Henny van Straaten; Peter van Breda Vriesman; Bernard Boneu; Philippe Druet; Abdelhadi Saoudi

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
130 KB
Volume
31
Category
Article
ISSN
0014-2980

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We have produced T cell lines with a Th2 phenotype in the presence of IL-4 and the glucocorticoid dexamethasone (DEX). IL-4 and DEX together were more effective in inducing a Th2 response than IL-4 alone. Myelin basic protein (MBP)-specific Th2 lines were obtained and their ability to induce experim