Essential role of placental leucine aminopeptidase in gynecologic malignancy
โ Scribed by Mizutani, Shigehiko; Shibata, Kiyosumi; Kikkawa, Fumitaka; Hattori, Akira; Tsujimoto, Masafumi; Ishii, Masakazu; Kobayashi, Hiroshi
- Book ID
- 121237889
- Publisher
- Informa plc
- Year
- 2007
- Tongue
- English
- Weight
- 194 KB
- Volume
- 11
- Category
- Article
- ISSN
- 1472-8222
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๐ SIMILAR VOLUMES
Leucine aminopeptidase (LAP) isoenzymes have been studied in the serum and urine of 53 consecutive patients with various types of malignant neoplastic disease, and compared with those in a group of 23 normal controls. Statistical evaluation and clinical correlation was made of the incidence and degr
In several recent studies, we have shown that P-LAP can be a poor prognostic factor and a factor of chemoresistance in endometrial carcinoma, especially in the advanced patients. In our study, we investigated whether P-LAP alters the expression of apoptosis regulatory proteins as a mechanism of drug