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Essential role of choline for pneumococcal virulence in an experimental model of meningitis

✍ Scribed by F. Gehre; S. L. Leib; D. Grandgirard; J. Kummer; A. Bühlmann; F. Simon; R. Gäumann; A. S. Kharat; M. G. Täuber; A. Tomasz


Book ID
108862472
Publisher
John Wiley and Sons
Year
2008
Tongue
English
Weight
358 KB
Volume
264
Category
Article
ISSN
0954-6820

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## Abstract An experimental model of meningeal leukemia in rats is developed by intracerebral (IC) inoculation of leukemic cells from the transplantable acute leukemia L5222. The L5222 proliferates exponentially in the central nervous system (CNS) and the disease becomes systemic 2 days following I