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Essential role of cell cycle regulatory genes p21 and p27 expression in inhibition of breast cancer cells by arsenic trioxide

✍ Scribed by Xi Wang; Ping Gao; Min Long; Fang Lin; Jun-Xia Wei; Ji-Hong Ren; Lin Yan; Ting He; Yuan Han; Hui-Zhong Zhang


Book ID
107577172
Publisher
Springer US
Year
2010
Tongue
English
Weight
557 KB
Volume
28
Category
Article
ISSN
1357-0560

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The expression and prognostic role of cyclin D1, cyclin E, and p21 (WAF1/CIP1) were immunohistochemically investivated in 413 curatively resected gastric carcinomas. p21 was expressed in 65β€’4 per cent (n=270), cyclin D1 in 23β€’7 per cent (n=98), and cyclin E in 13β€’6 per cent (n=56) of the tumours. Th