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Essential role for gene profiling analysis in the authentication of human cell lines

✍ Scribed by Kaori YOSHINO; Emi IIMURA; Kaoru SAIJO; Shigeru IWASE; Kaoru FUKAMI; Tadao OHNO; Yuichi OBATA; Yukio NAKAMURA

Book ID: 111390397
Publisher: John Wiley and Sons
Year: 2006
Tongue: English
Weight: 180 KB
Volume: 19
Category: Article
ISSN: 0914-7470
DOI: 10.1111/j.1749-0774.2005.00007.x

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## Abstract Gene amplification/overexpression was analyzed in 23 cell lines derived from human esophageal squamous‐cell‐carcinoma tissues by Southern and Northern hybridizations to c‐__myc__, c‐__erb__B, __hst__‐1 and __cyclin__‐DI probes. Amplification of the c‐__myc__ gene was observed in 5 cell