MHC class II-associated invariant chain
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Georg Malcherek; Christoph Wirblich; Nicholas Willcox; Hans-Georg Rammensee; Joh
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Article
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1998
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John Wiley and Sons
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English
⚖ 198 KB
Proteolysis of the invariant chain (li) leads to the generation of abundant MHC class II-associated invariant chain peptides (CLIP), which bind in the MHC class II binding groove via supermotifs in a manner similar to that of antigenic peptides. We have engineered an li vector with the capacity to e