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Erythropoietin receptor-mediated Egr-1 activation: Structural requirements and functional implications

✍ Scribed by Christoph Schulze; Tom Büchse; Stefan Mikkat; Thomas Bittorf


Book ID
113528213
Publisher
Elsevier Science
Year
2008
Tongue
English
Weight
636 KB
Volume
20
Category
Article
ISSN
0898-6568

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## Abstract We report here a role for cyclic AMP‐responsive element‐binding protein‐1 (CREB‐1) in B cell antigen receptor (BCR)‐induced growth inhibition by IFN‐γ. BCR‐induced proliferation is negatively regulated by IFN‐γ. Stimulation through BCR resulted in dose‐dependent induction of CREB‐1 bind