Enhancement of susceptibility to diverse
β
Erik Wilker; David Bol; Kaoru Kiguchi; Tim Rupp; Linda BeltrΓ‘n; John DiGiovanni
π
Article
π
1999
π
John Wiley and Sons
π
English
β 643 KB
Insulin-like growth factor-1 (IGF-1) and its receptor are believed to play an important role in mitogenesis and neoplastic transformation. The purpose of this study was to further examine the role of IGF-1 during tumor promotion in mouse skin. HK1.IGF1 transgenic mice, which overexpress IGF-1 in epi