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Erythropoietin induction in Hep3B cells is not affected by inhibition of heme biosynthesis

โœ Scribed by Hyogo Horiguchi; H. Franklin Bunn


Book ID
117351252
Publisher
Elsevier Science
Year
2000
Tongue
English
Weight
397 KB
Volume
1495
Category
Article
ISSN
0167-4889

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Differential induction of heme oxygenase
โœ J. D. Lutton; J.-L. da Silva; S. Moqattash; A. C. Brown; R. D. Levere; Dr. N. G. ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 671 KB

In situ hybridization and Northern analysis of heme oxygenase (HO) mRNA was used to determine the induction and expression of HO by various environmental agents. Exposure of Hep3B cells to hemin (1 0 pM) for as little as 5 min resulted in significant production of HO transcripts and mRNA expression