Differential induction of heme oxygenase
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J. D. Lutton; J.-L. da Silva; S. Moqattash; A. C. Brown; R. D. Levere; Dr. N. G.
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Article
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1992
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John Wiley and Sons
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English
โ 671 KB
In situ hybridization and Northern analysis of heme oxygenase (HO) mRNA was used to determine the induction and expression of HO by various environmental agents. Exposure of Hep3B cells to hemin (1 0 pM) for as little as 5 min resulted in significant production of HO transcripts and mRNA expression