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Erythropoietin for the treatment of anemia associated with hematological malignancy

✍ Scribed by T. J. Littlewood

Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
152 KB
Volume
19
Category
Article
ISSN
0278-0232

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✦ Synopsis

Abstract

Anemia is common in patients with hematological malignancy. Most patients will have their anemia attributed to the anemia of chronic disease. The anemia of chronic disease is caused by cytokine mediated suppression of erythropoiesis and low serum erythropoietin levels are found in the majority of patients with cancer. Many of these anemic patients will be symptomatic with fatigue. Data from many studies indicates that treatment of anemic patients with erythropoietin will increase their hemoglobin concentration, decrease transfusion need and also improve their quality of life. A recent study also suggests that improving the hemoglobin level may improve the patients' prognosis but this finding needs to be confirmed. Copyright Β© 2001 John Wiley & Sons, Ltd.

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✍ LeΓ³n, Pedro; JimΓ©nez, Miguel; Barona, Pascual; SierrasesΓΊmaga, Luis πŸ“‚ Article πŸ“… 1998 πŸ› John Wiley and Sons 🌐 English βš– 93 KB πŸ‘ 2 views

## Background. Cancer is often associated with chronic anemia which frequently requires blood transfusions. This study was performed to assess the efficacy and safety of r-HuEPO therapy in children with cancer. Patients and methods. Twenty-five patients under 18 years of age with solid malignant